Bioinformatics BI_D0004

Title : New trends in bioinformatics: from genome sequence to personalized medicine
Author :Robert Molidor, Alexander Sturn, Michael Maurer, Zlatko Trajanoski
Year : 2003
Place of publish :
Abstract :

 Molecular medicine requires the integration and analysis of genomic, molecular, cellular, as well as clinical data and it thus offers a
remarkable set of challenges to bioinformatics. Bioinformatics nowadays has an essential role both, in deciphering genomic, transcriptomic,
and proteomic data generated by high-throughput experimental technologies, and in organizing information gathered from traditional
biology and medicine. The evolution of bioinformatics, which started with sequence analysis and has led to high-throughput whole genome
or transcriptome annotation today, is now going to be directed towards recently emerging areas of integrative and translational genomics, and
ultimately personalized medicine.
Therefore considerable efforts are required to provide the necessary infrastructure for high-performance computing, sophisticated
algorithms, advanced data management capabilities, and-most importantly well trained and educated personnel to design, maintain and use
these environments.
This review outlines the most promising trends in bioinformatics, which may play a major role in the pursuit of future biological
discoveries and medical applications.